Vivinox инструкция по применению - Kompot.top - полезные статьи обо всем

Обычная доза для взрослых от бессонницы

Примечание: Acetaminophen-Vivinox Sleep Stark обычно дозируется на основе компонента Vivinox Sleep Stark до 50 мг Vivinox Sleep Stark (76 мг цитрата Vivinox Sleep Stark) перед сном.

Ацетаминофен-Вивинокс Sleep Stark выпускается в нескольких различных дозировках (500 мг-25 мг, 650 мг-50 мг, 500 мг-38 мг, 500 мг-12,5 мг, 1000 мг-50 мг, 500 мг-50 мг, 325 мг-12,5 мг) и гель в виде жидкости, капсулы. Производитель этих продуктов обычно советует 2 дозировки перед сном или по указанию медицинского работника.

Обычная доза для взрослых от боли

Обычная доза для головной боли

Обычная детская доза для бессонницы

Больше или равно 12 годам:

Обычная педиатрическая доза от боли

Больше или равно 12 годам:

Обычная детская доза при головной боли

Больше или равно 12 годам:

Корректировки почечной дозы

Данные недоступны

Корректировки дозы в печени

Используйте с осторожностью у пациентов с заболеваниями печени. Хроническое использование ацетаминофена не рекомендуется у пациентов с заболеваниями печени.

Меры предосторожности

Пациенты, которые употребляют три или более алкогольных напитка в день, должны быть проинформированы, чтобы проконсультироваться со своим врачом о том, когда и как принимать ацетаминофен. Хронические, тяжелые потребители алкоголя могут подвергаться повышенному риску повреждения печени при приеме более чем рекомендуемых доз.

Пациентам и взрослым, ухаживающим за детьми, следует посоветоваться с врачом, прежде чем продолжать использовать ацетаминофен, если симптомы болезни ухудшаются. Хотя это редко, существует вероятность ацетаминофен-интоксикации при хроническом применении препарата, и симптомы, наблюдаемые во время первой фазы интоксикации (тошнота, рвота, анорексия, недомогание и диафорез), могут вызывать использование большего количества доз.

Пациентов следует предупредить о седативных эффектах Vivinox Sleep Stark и рекомендовать не принимать этот препарат с алкоголем.

Из-за антихолинергического эффекта Vivinox Sleep Stark его следует использовать с осторожностью у пациентов с узкоугольной глаукомой, стенозирующей язвенной болезнью, пилородуоденальной обструкцией, гипертрофией предстательной железы или препятствиями шейки мочевого пузыря. Его также следует использовать с осторожностью у пациентов с повышенным внутриглазным давлением, гипертиреозом, сердечно-сосудистыми заболеваниями или гипертонией.

Диализ

Данные недоступны

Источник

Poor or restless sleep, lying awake for a long time at night, not feeling refreshed and fatigued in the morning and during the day — these problems are familiar to many people with sleep problems. The sleep problems can have different causes such as stress, shift work, various illnesses, etc. In the long run, sleep problems or insomnia can lead to poor physical and mental performance, irritability, difficulty concentrating, headaches and poor general mood.

VIVINOX Sleep sleeping tablets strong contain diphenhydramine, an H1 antihistamine, which causes drowsiness. The tablets can be taken by adults for a short time about 15 to 30 minutes before going to bed.

Application notes VIVINOX Sleep sleeping tablets strong

The total dose should not be exceeded without consulting a doctor or pharmacist.

How to use?
Take the medicine with liquid (e.g. 1 glass of water).

Duration of use?
The medicine should not be used for longer than 2 weeks. As a rule, however, the duration of treatment should be as short as possible and only last a few days. If symptoms persist for longer, you should consult your doctor.

Overdose?
In the event of an overdose, drowsiness, impaired consciousness, hallucinations and cardiovascular disorders may occur. If you suspect an overdose, contact a doctor immediately.

As a general rule: Pay particular attention to conscientious dosing for infants, small children and older people. If in doubt, ask your doctor or pharmacist about any effects or precautions.

A dosage prescribed by a doctor may differ from the information on the package leaflet. As the doctor will adjust it individually, you should therefore use the medicine according to his instructions.

Dosage
General dosage recommendation:
Adults 1 tablet once a day before going to bed (approx. 30 minutes before)
After taking the tablet, a sufficient sleep period of 7-8 hours should be ensured.
Patients with liver or kidney dysfunction: In consultation with your doctor, you may need to reduce the single or total dose or increase the interval between doses.
Elderly and debilitated patients: In consultation with your doctor, you may need to reduce the single or total dose or increase the interval between doses.

Application areas VIVINOX Sleep sleeping tablets strong

The medicine should only be used if the sleep disorder is severe and cannot be remedied in the short term by other measures, such as eliminating the cause.
— Sleep disorders, for short-term treatment

Mode of action VIVINOX Sleep sleeping tablets strong

How does the active ingredient of the medicine work?

The active ingredient blocks receptors for a specific messenger substance called histamine. This blockade suppresses histamine-induced vasodilation and increased blood flow in the smallest hair vessels (capillaries). It also combats nausea via the same mechanism and has a calming and sleep-promoting effect.

Composition VIVINOX Sleep sleeping tablets strong

Based on 1 tablet
50 mg diphenhydramine hydrochloride
43.75 mg diphenhydramine
+ cellulose, microcrystalline
+ lactose
+ povidone K25
+ silicon dioxide
+ magnesium stearate
+ crospovidone

Contraindications VIVINOX Sleep sleeping tablets strong

What speaks against an application?

Always:
— Hypersensitivity to the ingredients
— Heart disease, e.g:
— Coronary heart disease (circulatory disorders of the heart muscle)
— Deviation in the ECG (prolongation of the QT duration)
— Conduction disorders of the heart
— Cardiac arrhythmia
— Pulse rate reduction
— epilepsy
— Prostate enlargement with residual urine formation
— Difficulties urinating
— Pheochromocytoma (adrenaline-producing tumor)
— Disorders of the salt balance, such as
— Potassium deficiency
— magnesium deficiency
— Narrow-angle glaucoma
— Bronchial asthma, especially during an acute attack
— Gastric ulcer (ulcus ventriculi)
— Duodenal ulcer (Ulcus duodeni)
— Narrowed gastrointestinal passage

Under certain circumstances — talk to your doctor or pharmacist about this:
— Constriction in the digestive tract, such as:
— Achalasia (narrowing of the esophagus)
— Pyloric stenosis (narrowing of the stomach)
— Chronic obstructive airway disease (chronic airway disease with a narrowing of the airways)
— Impaired kidney function
— Impaired liver function

Which age group should be considered?
— Children and adolescents under 18 years of age: The medicine should not generally be used in this age group.

What about pregnancy and breastfeeding?
— Pregnancy: The medicinal product must not be used.
— Breastfeeding: The medicine must not be used.

If you have been prescribed the medicine despite a contraindication, talk to your doctor or pharmacist. The therapeutic benefit may be greater than the risk associated with the use of a contraindication.

Side effects VIVINOX Sleep sleeping tablets strong

What adverse effects can occur?

— Gastrointestinal complaints, such as
— Nausea
— vomiting
— diarrhea
— constipation
— heartburn
— Dry mouth
— headaches
— dizziness
— drowsiness
— drowsiness
— Concentration problems
— Strange (paradoxical) reactions, such as
— restlessness
— nervousness
— excitement
— states of anxiety
— trembling
— sleep disturbances
— visual disturbances
— Increase in intraocular pressure
— Allergic reactions
— Increased sensitivity of the skin to light
— Deviation in the ECG (prolongation of the QT duration)
— Urination disorders
— Bile stasis with development of jaundice
— Change in the blood count

If you notice any discomfort or change during treatment, contact your doctor or pharmacist.

The information provided here is based primarily on side effects that occur in at least one in 1,000 patients treated.

Hints VIVINOX Sleep sleeping tablets strong

What should you bear in mind?
— The ability to react may be impaired even when used as intended, especially in higher doses or in combination with alcohol. Pay particular attention when driving or operating machinery (including household machinery) that could cause injury.
— Avoid excessive UV radiation, e.g. in solariums or during extended sunbathing, because the skin reacts more sensitively during the use of the medicine.
— Sudden discontinuation may cause problems or discomfort. Treatment should therefore be stopped slowly, i.e. by gradually reducing the dose. It is best to seek advice from your doctor or pharmacist.
— Caution: If you use the medicine for a long time, the body may become accustomed to it and you may need an increasingly higher dosage in order to feel an effect.
— Take care if you are intolerant to lactose. If you have to follow a diabetes diet, you should take the sugar content into account.
— There may be medicines with which interactions occur. You should therefore always tell your doctor or pharmacist about any other medicine you are already taking before starting treatment with a new medicine. This also applies to medicines that you buy yourself, use only occasionally or have been using for some time.

Источник

Vivinox is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.

Vivinox has anti-histaminic (H1-receptor), anti-emetic, anti-vertigo and sedative and hypnotic properties . The anti-histamine action occurs by blocking the spasmogenic and congestive effects of histamine by competing with histamine for H1 receptor sites on effector cells, preventing but not reversing responses mediated by histamine alone . Such receptor sites may be found in the gut, uterus, large blood vessels, bronchial muscles, and elsewhere . Anti-emetic action is by inhibition at the medullary chemoreceptor trigger zone . Anti-vertigo action is by a central antimuscarinic effect on the vestibular apparatus and the integrative vomiting center and medullary chemoreceptor trigger zone of the midbrain .

Attribute	Details
Trade Name	Vivinox
Availability	Rx and/or OTC
Generic	Diphenhydramine
Diphenhydramine Other Names	Difenhidramina, Diphenhydramine, Diphenhydraminum
Related Drugs	Gocovri, prednisone, ibuprofen, acetaminophen, hydroxyzine, amitriptyline, lorazepam, ondansetron, cetirizine, loratadine
Type
Formula	C₁₇H₂₁NO
Weight	Average: 255.3547 Monoisotopic: 255.162314299
Protein binding	Some prescribing information records the protein binding of diphenhydramine as approximately 78% while others have suggested the medication is about 80 to 85% bound to plasma proteins.
Groups	Approved, Investigational
Therapeutic Class	Sedating Anti-histamine
Manufacturer
Available Country	Germany
Last Updated:	January 7, 2025 at 1:49 am

Uses

Vivinox is used for the treatment of followings:

Seasonal, perennial, vasomotor rhinitis
Urticaria, angioneurotic oedema, anaphylaxis
Pruiritic conditions
Premedication for emesis and motion sickness
Miscellaneous like meniere’s disease and parkinsonism

Vivinox is also used to associated treatment for these conditions:
Allergic Rhinitis (AR), Allergic cough, Allergies, Anaphylaxis, Angioedema, Common Cold, Common Cold/Flu, Conjunctival irritation, Cough, Cough Variant Asthma, Cough caused by Common Cold, Eye allergy, Fever, Insect Bites, Insect Stings, Insomnia, Irritative cough, Itching of the nose, Itching of the throat, Motion Sickness, Nasal Congestion, Oral Mucositis, Pain, Parkinsonian Syndromes, Pollen Allergy, Productive cough, Pruritus, Rash, Rhinorrhoea, Sinus Congestion, Sinus headache, Skin Irritation, Sneezing, Sunburn, Symptoms of Acute Bronchitis Accompanied by Coughing, Upper respiratory tract hypersensitivity reaction, site unspecified, Urticaria, Dermatographism, Dry cough, Watery itchy eyes, Airway secretion clearance therapy, Expectorant

How Vivinox works

Vivinox predominantly works via the antagonism of H1 (Histamine 1) receptors . Such H1 receptors are located on respiratory smooth muscles, vascular endothelial cells, the gastrointestinal tract (GIT), cardiac tissue, immune cells, the uterus, and the central nervous system (CNS) neurons . When the H1 receptor is stimulated in these tissues it produces a variety of actions including increased vascular permeability, promotion of vasodilation causing flushing, decreased atrioventricular (AV) node conduction time, stimulation of sensory nerves of airways producing coughing, smooth muscle contraction of bronchi and the GIT, and eosinophilic chemotaxis that promotes the allergic immune response .

Ultimately, diphenhydramine functions as an inverse agonist at H1 receptors, and subsequently reverses effects of histamine on capillaries, reducing allergic reaction symptoms . Moreover, since diphenhydramine is a first-generation antihistamine, it readily crosses the blood-brain barrier and inversely agonizes the H1 CNS receptors, resulting in drowsiness, and suppressing the medullary cough center .

Furthermore, H1 receptors are similar to muscarinic receptors . Consequently, diphenhydramine also acts as an antimuscarinic . It does so by behaving as a competitive antagonist of muscarinic acetylcholine receptors, resulting in its use as an antiparkinson medication .

Lastly, diphenhydramine has also demonstrated activity as an intracellular sodium channel blocker, resulting in possible local anesthetic properties .

Dosage

Adult-

Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.

Children-

1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day

Side Effects

Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.

Toxicity

Overdose is expected to result in effects similar to the adverse effects that are ordinarily associated with the use of diphenhydramine, including drowsiness, hyperpyrexia, and anticholinergic effects, among others . Additional symptoms during overdose may include mydriasis, fever, flushing, agitation, tremor, dystonic reactions, hallucinations and ECG changes . Large overdose may cause rhabdomyolysis, convulsions, delirium, toxic psychosis, arrhythmias, coma and cardiovascular collapse . Moreover, with higher doses, and particularly in children, symptoms of CNS excitation including hallucinations and convulsions may appear; with massive doses, coma or cardiovascular collapse may follow .

Although diphenhydramine has been in widespread use for many years without ill consequence, it is known to cross the placenta and has been detected in breast milk . This medication should therefore only be used when the potential benefit of treatment to the mother exceeds any possible hazards to the developing fetus or suckling infant .

Pharmacokinetic studies indicate no major differences in the distribution or elimination of diphenhydramine compared to younger adults . Nevertheless, diphenhydramine should be used with caution in the elderly, who are more likely to experience adverse effects . Avoid use in elderly patients with confusion .

The results of a review on the use of diphenhydramine in renal failure suggest that in moderate to severe renal failure, the dose interval should be extended by a period dependent on Glomerular filtration rate (GFR) .

After intravenous administration of 0.8 mg/kg diphenhydramine, a prolonged half-life was noted in patients with chronic liver disease which correlated with the severity of the disease . However, the mean plasma clearance and apparent volume of distribution were not significantly affected .

LD₅₀=500 mg/kg (orally in rats). Considerable overdosage can lead to myocardial infarction (heart attack), serious ventricular dysrhythmias, coma and death.

Precaution

Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.

Interaction

Vivinox administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Vivinox. Anticholinergic drugs may potentiate Vivinox’s anticholinergic side effects.

Food Interaction

Avoid alcohol.
Take before a meal. Take 30 minutes before a meal or 30 minutes before departure for motion sickness.

Vivinox Alcohol interaction

[Moderate] GENERALLY AVOID:

Use of anticholinergic agents with alcohol may result in sufficient impairment of attention so as to render driving and operating machinery more hazardous.

In addition, the potential for abuse may be increased with the combination.

The mechanism of interaction is not established but may involve additive depressant effects on the central nervous system.

No effect of oral propantheline or atropine on blood alcohol levels was observed in healthy volunteers when administered before ingestion of a standard ethanol load.

However, one study found impairment of attention in subjects given atropine 0.5 mg or glycopyrrolate 1 mg in combination with alcohol.

Alcohol should generally be avoided during therapy with anticholinergic agents.

Patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.

Drug Interaction

Moderate: duloxetine, duloxetine, pregabalin, pregabalin, alprazolam, alprazolam, cetirizine, cetirizineUnknown: aspirin, aspirin, omega-3 polyunsaturated fatty acids, omega-3 polyunsaturated fatty acids, acetaminophen, acetaminophen, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol

Disease Interaction

Major: depressionModerate: anticholinergic effects, asthma/COPD, cardiovascular, renal/liver disease, glaucoma, liver disease, resp depression

Volume of Distribution

Vivinox is widely distributed throughout the body, including the CNS . Following a 50 mg oral dose of diphenhydramine, the volume of distribution is in the range of 3.3 — 6.8 l/kg .

Elimination Route

Vivinox is quickly absorbed after oral administration with maximum activity occurring in approximately one hour . The oral bioavailability of diphenhydramine has been documented in the range of 40% to 60%, and peak plasma concentration occurs about 2 to 3 hours after administration .

Half Life

The elimination half-life ranges from 2.4-9.3 hours in healthy adults . The terminal elimination half-life is prolonged in liver cirrhosis .

Clearance

Values for plasma clearance of a 50 mg oral dose of diphenhydramine has been documented as lying in the range of 600-1300 ml/min .

Elimination Route

The metabolites of diphenhydramine are conjugated with glycine and glutamine and excreted in urine . Only about 1% of a single dose is excreted unchanged in urine . The medication is ultimately eliminated by the kidneys slowly, mainly as inactive metabolites .

Pregnancy & Breastfeeding use

Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Vivinox hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.

Contraindication

Known hypersensitivity to Vivinox Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.

Acute Overdose

Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical).

Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.

Storage Condition

Store between 15-30° C. Protect from moisture.

Innovators Monograph

FAQ

What is Vivinox used for?

Vivinox is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness.

How safe is Vivinox?

The U.S. Food and Drug Administration is warning that taking higher than recommended doses of the common over-the-counter (OTC) allergy medicine diphenhydramine can lead to serious heart problems, seizures, coma, or even death.

How does Vivinox work?

Vivinox works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

What are the common side effects of Vivinox?

Common side effects of Vivinox are include:

dry mouth, nose, and throat
drowsiness
dizziness
nausea
vomiting
loss of appetite
constipation
increased chest congestion
headache
muscle weakness
excitement (especially in children)
nervousness

Is Vivinox safe during pregnancy?

Vivinox is considered to be safe during pregnancy. Doctors and nurses recommend this OTC medication to help relieve allergy symptoms, even while you’re pregnant. Recent studies have found Vivinox to be safe.

Is Vivinox safe during breastfeeding?

Small, occasional doses of Vivinox would not be expected to cause any adverse effects in breastfed infants.

Can I drink alcohol with Vivinox?

Alcohol may increase drowsiness and dizziness while you are taking Vivinox. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination.

Can I drive after taking Vivinox?

Do not drive or operate machinery if Vivinox makes you drowsy or affects your judgment.

When should be taken of Vivinox?

When Vivinox is used to treat motion sickness, it is usually taken 30 minutes before departure and, if needed, before meals and at bedtime.

How often can I take Vivinox?

Vivinox is usually taken every 4 to 6 hours.

How much Vivinox can I take in a day?

For adults and teens, the Vivinox dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness.

Is Vivinox bad for my liver?

Despite widespread use over many decades, Vivinox has not been linked to liver test abnormalities or to clinically apparent liver injury. The reason for its safety may relate its short half-life and limited duration of use.

How long does Vivinox take to work?

It normally takes about 30 minutes to work. Common side effects include feeling sleepy, dizzy or unsteady on your feet. You may also have difficulty concentrating and have a dry mouth.

Can I take Vivinox on an empty stomach?

Vivinox may be taken with or without food. Take exactly as directed. Do not take more than is recommended.

How long does Vivinox stay in my system?

A half-life of a drug determines how long it will take for 50% of it to flush out of your system. Depending on the median value that the individual lands on, Vivinox can stay in your system anywhere between 13.2 and 49 hours.

Can Vivinox be taken long-term?

Caution should be exercised for long-term use of Vivinox, an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia.

How long can I use Vivinox?

Do not use Vivinox for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.

Who should not take Vivinox?

If you have increased pressure in the eye, closed angle glaucoma, high blood pressure, stenosing peptic ulcer you should not take Vivinox.

What happen If I suddenly stop taking Vivinox?

Although withdrawal symptoms of Vivinox are minor compared to harder drugs, you may experience cold sweats, nausea, or diarrhea when stopping the drug suddenly.

What happen If I missed Vivinox?

Since Vivinox is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happen if I take too much Vivinox?

Taking more than the normal Vivinox dosage can be harmful. Serious side effects from too much of the Vivinox can include nausea, vomiting, blurred vision, trouble breathing, hallucinations, unconsciousness, and seizures.

Can Vivinox cause heart problems?

Taking too much Vivinox can lead to serious heart problems, seizures, coma, or death.

Can Vivinox cause heart palpitations?

A fast heartbeat is a common side effect of Vivinox. In rare cases, it can become serious.

Can Vivinox damage kidneys?

In general, Vivinox do not cause kidney problems.

*** Taking medicines without doctor’s advice can cause long-term problems.

Источник

Общие сведения о vivinox® ночного сна драже

Идеально подходит для людей, которые предпочитают при бессонницы надежный растительный препарат. vivinox® ночного сна драже объединить полезные свойства валерианы и хмеля. С их высокой концентрации активных веществ они способствуют расслаблению вечером и естественного, спокойного и глубокого сна. Они хорошо переносятся на спа-процедуры подходят и нет эффекта привыкания.

Состав vivinox® ночного сна драже

1 табл. содержит

Активные ингредиенты

45 мг 5,5-6,5:1) шишки хмеля экстракта сухого (; Выписка средство: вода
187.50 мг валерианы корня экстракта сухого (5,3-6,6:1); Выписка средство: метанол 45% (m/m)

Вспомогательные вещества

Кальций(пальмитат,стеарат)
Кроскармеллоза натрия
Мальтодекстрин
Карнаубский воск
Железо(II,III) оксид
Оксиды и гидроксиды железа
Тон, белый
Диоксид кремния, высокой disperses
Кукурузный крахмал, leistert pre
Бензоат натрия
Повидон К30
Желтый Оранжевый S, Алюминиевая Соль
Бутилметакрилата сополимер, щелочная
Железо(III) оксид
Понсо 4R-алюминиевая соль
Гидроксид натрия
Сахароза
Кукурузный крахмал
Метил-4-гидрокси-бензоата
Propyl 4-hydroxybenzoate
Макрогол 6000
Диоксид титана
Воск, отбеленное
Арабское Резина
Карбонат кальция
Тальк

Применение области vivinox® ночного сна драже

— Нервно родственные разлады сна
— Беспокойство

Дозировка vivinox® ночного сна драже

Принимайте препарат всегда точно в соответствии с инструкцией в данном листке-вкладыше. Пожалуйста, не спросите у своего врача или фармацевта, если вы точно знаете.
Если врач не назначил другое, обычная доза составляет:
- Для взрослых и детей старше 12 лет для лечения Беспокойства 1 раз в день 1 покрынные таблетки (драже), для лечения бессонницы нервных условного покрынные 1 таблетке (драже) 1/2 до 1 часа перед сном.
Пожалуйста, поговорите со своим врачом или фармацевтом, если у вас сложилось впечатление, что действие этого лекарственного средства слишком сильным или слишком слабым.

Длительность применения
- Длительность применения препарата не является в принципе ограниченным. При Остановке жалоб через 2 недели или при обострении нужно принимать посоветовавшись с врачом.

Если вы взяли большую сумму, чем вы должны
- Если вы случайно заняли даже двойной или тройной, предусмотренных дозировка (соответствует 2 — 3 покрынные таблетки (драже) этого препарата), так что это не оказывает, как правило, негативным последствиям. Продолжайте в этом случае прием так, как это в соответствии с инструкциями дозировки или врачом не было предписано.
- Если вы перебирали этот препарат значительно, вы должны проконсультироваться с врачом.

Если вы забыли прием
- Не принимайте двойную дозу, а продолжайте принимать или применения так, как это указано в данном вкладыше или врачом не было предписано.

При отмене приема
- С помощью данной процедуры можно поставить под угрозу успех лечения.

Другая информация о vivinox® ночного сна драже

— Когда нервничает родственных бессонница и/или беспокойство длиться дольше, следует обратиться к, как и во всех жалобах, врач.

Противопоказания к vivinox® ночного сна драже

Против всех лекарств могут возникнуть реакции Гиперчувствительности, то вы должны остановить прием препарата немедленно. Если уже есть аллергия к активному веществу или любому из вспомогательных веществ препарата, как известно, не может быть применен.

Беременность и период лактации vivinox® ночного сна драже

Во время беременности и грудного вскармливания вы должны принимать лекарства возможно только после консультации с вашим врачом или фармацевтом!

— Из распространенных применение корня валерианы в качестве лекарственных средств были сделаны до сих пор нет доказательств риска в период беременности и лактации.
— Исследования, но не. Поэтому препарат следует принимать во время беременности и в период лактации только после консультации с врачом.

Приложение vivinox® ночного сна драже

— Драже с небольшим количеством жидкости занимать.

Читать о противопоказаниях и побочных вкладыш упаковки и обратитесь к врачу или фармацевту.

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Diphenhydramine (brand: Vivinox) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can cause symptoms such as sneezing, itching, watery eyes and runny nose.

Diphenhydramine (Vivinox) is used to treat

Sneezing,
Watery eyes,
Runny nose,
Skin rash,
Hives,
Itching, and
other cold or allergy symptoms.

Diphenhydramine is also used to treat

Motion sickness,
To induce sleep, and
To treat certain symptoms of Parkinson’s disease.

Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.

Vivinox Mechanism

Diphenhydramine (Vivinox) competes with free histamine for binding to HA receptor sites. This antagonizes the effects of histamine on HA receptors, which leads to a reduction in negative symptoms caused by the binding of the histamine HA receptor.

This drug blocks some natural substance (histamine) that your body forms during an allergic reaction. Its dehydrating effect on symptoms such as watery eyes and nasal discharge is caused by the blockage of another natural substance (acetylcholine).

Following are some of the side effects associated with the use of vivinox

Drowsiness,
Dizziness,
Constipation,
Stomach upset,
Blurred vision, or
Dry mouth/nose/throat may occur.

If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Contraindications

Vivinox is contraindicated in

Hypersensitivity to diphenhydramine or any other ingredients in vivinox.
Closure glaucoma,
Prostatic hypertrophy,
Stenosing peptic ulcer,
Stenosis of the bladder neck,
Epilepsy
Bronchial asthma.

Vivinox In Pregnancy

Diphenhydramine is a category B drug this means that Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.Thats why Should be used with caution in pregnancy.

Dosage and administration

Available in Oral, IV, IM, rectal, topical, intranasal, in the conjunctival sac.
Usual Oral dose for adults is 30-50 mg 1-3 times / day. The treatment course is 10-15 days.
IM in doses of 50-250 mg;
IV in drip – 20-50 mg.
When oral administered single dose for children under 1 year – 2-5 mg;
Usual dose for 2 to 5 years of age- 5-15 mg; of 6 to 12 years – 15-30 mg.
Externally applied 1-2 times / day.

Vivinox interactions with Other Drugs

Certain Drugs Increase or decrease the effects of other drugs when use concomitantly.

Diphenhydramine (Vivinox) simultaneous use with Mono Amine Oxidase inhibitors increase the anticholinergic activity of diphenhydramine.

When applied simultaneously increases the effects of ethanol and drugs that depress the central nervous system.

The antagonistic interaction observed with a joint appointment with psychostimulants.

Intensifies anticholinergic effects of drugs with anticholinergic activity.

Reduces the effectiveness of apomorphine as an emetic in the treatment of poisoning.

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