Disodium hydrogen citrate syrup инструкция - Kompot.top - полезные статьи обо всем

Description

Disodium Hydrogen Citrate is a drug that is associated with citric acid. Citric acid is commonly used in the pharmaceutical and food industries. Citric acid is a weak organic acid that is found in citrus fruits like oranges, lemons, and limes. Disodium Hydrogen Citrate is created by combining citric acid with sodium hydroxide and water. This syrup has several health benefits due to its antioxidant properties. Antioxidants are substances that protect the body from damage caused by harmful molecules called free radicals. Free radicals can cause damage to cells and lead to diseases like cancer, heart disease, and Alzheimer’s disease. Disodium Hydrogen Citrate helps to neutralize free radicals and prevent them from causing harm.

This syrup is used to treat a variety of health problems such as tubular acidosis, Kidney and Gout stone, Gastric problems, Acidity, Constipation, and Abdominal gas. Commonly this syrup is used as an acidity regulator and it also flushes out extra uric acid from the blood through urine because of its antioxidant property. In our advice, while using this syrup please follow proper precautions and instructions. If you experience any of these side effects so please get in touch with your doctor.

How to Use Disodium Hydrogen Citrate Syrup

Disodium Hydrogen Citrate Syrup is a medicine that is commonly used to treat kidney stones and Gout stones, Gas, and Acidity problems. The dosage of this medicine depends on the patient’s age, weight, and medical conditions. However here are a few instructions to use this medicine.

Measure the syrup using a measuring cup or spoon.
Dilute the syrup in water before consuming it.
Drink plenty of water while taking the syrup to prevent the formation of kidney stones.
Take the syrup as directed by your doctor.
Shake the bottle before use.

Benefits

Disodium Hydrogen Citrate Syrup is a medication commonly used to treat urinary tract infections and other conditions that affect the urinary system. Here are some of the benefits of using Disodium Hydrogen Citrate Syrup:

Kidney stone and Gout stone: This syrup has antioxidant properties and Citric acid that help to reduce the problem of kidney stone and gout stone.

Alleviates Pain and Burning Sensations: It helps to reduce pain, discomfort, and burning sensations during urination by increasing the pH of urine, making it less acidic.

Prevents Urinary Tract Infections: This medicine can reduce urine passing problems or urinary tract infections by reducing the bad germs in the urinary area.

Promotes Kidney Function: By increasing urine output, Disodium Hydrogen Citrate Syrup can help promote kidney function and prevent complications associated with kidney disease.

Easy to Consume: Disodium Hydrogen Citrate Syrup is easy to Consume, and it is available in a liquid form, making it easier for children and elderly patients to take.

Side effects

Disodium Hydrogen Citrate Syrup is used to treat so many health problems in the human body. However, like other Mordan medicines, it causes some side effects. Here is the list of some common side effects you may experience while consuming this syrup:

Diarrhea
Nausea and vomiting
Tiredness
Frequent urge to urinate
Unpleasant taste
Stomach cramps
Excessive air or gas in the stomach
Change in mood

Precautions

Dosage: The patient can consume this syrup twice a day after food however it is important to take a doctor’s consultation before starting any medicine or the dosage may depend on the patient’s age weight or medical or health history.

Alcohol: Follow your doctor’s instructions and avoid alcohol. If you experience unusual symptoms, talk to your doctor right away.

Allergies: If you have allergies to citric acid and any other medicine so please tell your doctor before taking the treatment of this medicine.

FAQs

Ques. How many times we can consume Disodium Hydrogen Citrate Syrup?

Ans. You can consume this syrup two tablespoons twice a day or you also get in touch with your doctor for better consultation.

Ques. How long does disodium hydrogen citrate take to work?

Ans. It may take 4 to 6 hours to start working properly in your body.

Additional information

Brand Name	Flowurate
Composition	Disodium Hydrogen Citrate
Pack Size	100 ML

Источник

Therapeutic Indications

Disodium Hydrogen Citrate is an acidic salt that is used in making urine more alkaline. It is an alkalizing agent. It is a salt of citric acid. It is used in the treatment, control, and management of the following conditions, diseases, and symptoms:

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Gout
Urate kidney stones
Acidosis due to kidney disease
Burning micturition
Urinary tract infections
Acidosis due to diarrhea
An antioxidant
With sulphonamides in adjuvant therapy
Constipation
Abdominal complications
Gastric problems
Uterine tract infections
To improve the effects of other antioxidants

Do I Need a Prescription?

Disodium hydrogen citrate can be bought from pharmacies close to you and online drug stores. But a doctor’s prescription is mandatory.

Dosage

The dosage and duration of use for disodium hydrogen citrate depend on the medical condition, response to therapy and age. The recommended dosage is:

Adults: 15 to 30 ml two or three times a day when dissolved in water
Children 7 to 12 years: 5 ml two to three times a day when dissolved in water
Children below the age of 7 years: 2 ml three times a day dissolved in water

Chemical composition

The active ingredient in disodium hydrogen citrate syrup is disodium hydrogen citrate. It is a salt of citric acid.

Mechanism of Action (MOA)

Disodium hydrogen citrate works by removing excess uric acid from the blood through urine. The active ingredient once administered is metabolized and forms bicarbonate ions that neutralize acids in blood and urine, this makes urine to be more alkaline, and the pH is increased, lowering acidosis symptoms.

When the pH of urine is alkaline, micro-organism growth is hindered thus being able to relieve the symptoms of urinary tract infections and curing it. Disodium hydrogen citrate makes cysteine to be more soluble in urine and also makes ions of uric acid, urate ions, this prevents formations of kidney stones.

Contraindications

The use of disodium hydrogen citrate is contraindicated in some conditions. When used it could lead to the occurrence of an adverse reaction or make the medical condition severe that it is. Before taking disodium hydrogen citrate, inform your doctor of all medical conditions you have or have had before and those your family has a history of as they may affect the prescription. Disodium hydrogen citrate is not to be used if you have the following conditions:

Allergic reactions to the active ingredient disodium hydrogen citrate
Kidney dysfunction
Heart problems such as irregular heartbeat, heart failure, congestive heart failure, heart enlargement
Fluid retention in the body in the ankles. Legs or feet ( peripheral edema)
High blood pressure
On a diet with sodium restriction
High levels of sodium
A breathing problem such as pulmonary edema
Low levels of calcium
Diabetes as the product might contain sugar
Dehydration
A bacterial infection that is severe
Disodium hydrogen citrate is not advised to be used during pregnancy as it could harm the fetus.
Lactation, Disodium hydrogen citrate is not advised as it could harm the nursing baby.
Neonates
Addison’s disease
Toxemia of pregnancy
Crohn’s disease

Facts on Disodium Hydrogen Citrate

The effect of Disodium hydrogen citrate begins within a minute of administration.
The duration of effect of disodium hydrogen citrate lasts for 4 to 6 hours.
Disodium hydrogen citrate is also used as a food additive and as an anticoagulant.
It is manufactured by reacting sodium hydroxide and citric acid
It has not been shown to have any effects on fetus and nursing babies.
It is an antioxidant.

Side effects

Medications cause side effects apart from the intended results. Disodium hydrogen citrate causes side effects, but they do not occur in everybody. They depend on the duration of use, the dosage and individual reaction to the medication. The side effects can occur at the beginning of the treatment but go away on their own. The side effects can be common and less serious while others can be rare and very serious. Inform your doctor of any side effects you experience to get medical advice on how to cope with them and for medical attention for those that are serious. The following are the less serious and common side effects of disodium hydrogen citrate:

Stomach ache
Nausea
Vomiting
Weakness
Gastrointestinal discomfort
Bloating
A headache

Rare and serious side effects include:

Diarrhea that is severe and ongoing
Irritable
Nervous
Stomach ulceration
Mood swings
Seizures
Slow or fast heartbeat
Confusion
Increased urination
Reduced blood levels of potassium
Metabolic alkalosis
Dizziness
Shallow and rapid breathing
Bloody stool
Muscle twitching or pain
Cramps or leg pain
Peripheral edema
Numbness or tingling in the hands and legs
Irregular heartbeat

Nausea, vomiting, diarrhea, and pain in the stomach can be reduced by taking the medication after a meal, taking a lot of water and taking the drug with juice or plenty of water.

In case you have an allergic reaction to disodium hydrogen citrate, stop taking the medication and inform your doctor or seek medical attention urgently. Symptoms of an allergic reaction include difficulty breathing, severe dizziness, swelling of throat, lips, face and tongue and hives.

If you accidentally take an overdose of disodium hydrogen citrate, inform your doctor or rush into the emergency center of the nearest hospital carrying the medication package with you. Taking an overdose can result in adverse reactions that can be fatal. An overdose can cause loss of consciousness, muscle spasms, seizures, and metabolic alkalosis.

Drug Interactions

When you take more than one medication at the same time, it can result in the drugs interacting. Drug interactions can change the way your medication is working making it less effective or affects the working of the other medications you are taking. Drug interactions can also cause accumulation of drugs in the body that can cause adverse reactions to occur. Inform your doctor of all medications you are using or have been using both over the counter medications and prescription drugs, dietary supplements and herbal products. The following drugs and products interact with disodium hydrogen citrate:

Tetracycline, when used together increases their renal excretion.
Amphetamine
Quinidine
Ephedrine
Antacids containing aluminum and sodium, and baking powder (sodium bicarbonate) when used can cause a severe imbalance of electrolyte in the body or toxicity due to aluminum.
Lithium
Methenamine
Allergy medications and cold medications or decongestants
Diet Pills
ADHD medications
Mineral and vitamin supplements containing calcium
Medications that contain calcium
Salicylates like aspirin effects are lowered as their excretion is enhanced given that they are acidic drugs
Corticosteroids, it causes retention of sodium
Alcohol
Barbiturates, their excretion is enhanced when used together with disodium hydrogen citrate
Diuretics that deplete potassium, when used concurrently can cause hypochloraemia alkalosis

What to Do If You Skip a Dose?

If you skip a dose, take it as soon as you realize it. If it is time close to your next treatment, you can skip the dose and take your next dose then continue with the normal drug schedule. However, do not double the dose to compensate for the skipped dose as it will be an overdose that can result in adverse effects. Frequent missing does make your medication less effective in treating your condition. To avoid frequent dose missing set the alarm to remind you or have a family member remind you when it is time for your next dose.

Precautions

A number of precautions should be considered before you use and when using disodium hydrogen citrate. The precautions include:

Hypersensitive reactions: Do not use disodium hydrogen citrate if you are allergic to the active ingredient.
Inform your doctor of all medications and products you are using to avoid drug interactions that may be fatal.
Notify your doctor of all medical conditions you have or have had before to prevent them worsening or adverse reactions from occurring.
Pregnant or planning to be pregnant and lactating mothers should use disodium hydrogen citrate with cautions as there is no conclusive evidence of its effects on the growing fetus and nursing baby.
Renal impairment. If you have kidney disease, disodium hydrogen citrate should be used with caution. In very severe cases, the dose should be adjusted.
If you experience dizziness and drowsiness while using disodium hydrogen citrate, then you are advised not to engage in activities that require mental alertness such as driving and operation of heavy machinery.
Disodium hydrogen citrate should be taken after a meal with plenty of water to avoid stomach upset.
Avoid foods that contain a lot of salt and the use of extra table salt while using disodium hydrogen citrate as it already contains sodium.
While taking disodium hydrogen citrate, you should carry out frequent urine and blood test to ensure that the medication is working.
Disodium hydrogen citrate should be stored in a closed container, at room temperature away from moisture, sunlight, children and pets.
Do not increase or lower the dosage prescribed by your doctor. Taking large doses of disodium hydrogen citrate can affect the working of your kidney.
Avoid or reduce alcohol consumption while sing disodium hydrogen citrate, as alcohol, might lower its effects.
The syrup form of disodium hydrogen citrate contains sugar in it, thus use it with caution if you have diabetes.
The bottle of disodium hydrogen citrate should be well shook before measuring the dose using a measuring cup and not a tablespoon.
Do not take disodium hydrogen citrate that is expired. Its potency may have reduced making it less effective in treating your condition. Always check the medication package while purchasing the drug.

Different Brands and Manufacturing Companies of the Drug

Disodium hydrogen citrate is manufactured mainly as a syrup or a suspension. It is manufactured by different pharmaceutical companies and sold under different brand names. The different brands can be used as alternatives and substitutes. The different brand includes:

Cital – 1.37 mg/5 ml – Indoco Remedies Ltd
Siocitrate – 1.375g/5 ml – Albert David Limited
Oricitral – 1.38g/5 ml – TTK Healthcare Ltd
Alkaryl – 1.4 g/5 ml – Cadila Pharmaceuticals Ltd
Alkasol – 1.4 g/5 ml – Stadmed Private Limited
Citralka – 1.53 g/5 ml – Parke – Davis (India) Ltd
Biocetral – 1.53 gm – Bioguard Organics
Citra Sip Syrup – 1.20 gm – Kwality Pharmaceuticals (P) Ltd
Alkanil –Inga Pharmaceuticals Pvt Ltd
Alkarate – 1.37 g/5 ml – Macleods Pharmaceuticals Ltd(Pharma)
Citralka – 1.53 g/5 ml – Pfizer Limited
Systal – 1.38 g/ 5ml – Commonwealth Laboratories (India) Pvt Ltd.

References

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Disodium Hydrogen Citrate Medication Information

Discover comprehensive details about Disodium Hydrogen Citrate, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Disodium Hydrogen Citrate brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Disodium Hydrogen Citrate

Pronunciation : Di-SOE-dee-um- Hy-Dro-gen-SIT-rate

Therapeutic Classification :
Miscellaneous

Brand Names or Trade Names of Disodium Hydrogen Citrate

India :

Overview of Disodium Hydrogen Citrate

• Disodium hydrogen citrate is a urinary alkalinizer used for the treatment of renal tubular acidosis, to prevent uric acid and cysteine stones, and in the treatment of urinary tract infections.

Why is Disodium Hydrogen Citrate Prescribed? (Indications)

Disodium hydrogen citrate is a urinary alkalanizer.

It is used for the following conditions:
• Renal tubular acidosis (a condition where the blood is acidic due to a kidney problem)
• To prevent uric acid and cysteine stones in people predisposed to form the stones in the urinary tract
• To treat uterine tract infection, though evidence for the same has not been established

When should Disodium Hydrogen Citrate not be taken? (Contraindications)

Disodium hydrogen citrate should not be used in the following conditions:

• Allergy to the drug
• High blood pressure (since it contains sodium)
• Fluid accumulation in the body (called edema)
• Metabolic derangements like high osmolality or increased alkalinity of the blood, low blood calcium levels
• Kidney dysfunction

What is the dosage of Disodium Hydrogen Citrate?

• The usual dosage of the syrup in adults is 15 to 30 ml two to three times a day.

How should Disodium Hydrogen Citrate be taken?

• Take after a meal on a full stomach.

What are the warnings and precautions for Disodium Hydrogen Citrate?

• Drink plenty of water while on the medication.

• Inform your doctor if you are pregnant or breastfeeding before taking the medication.

What are the side effects of Disodium Hydrogen Citrate?

Digestive tract: Diarrhea, stomach pain, nausea, vomiting, bleeding from the stomach or intestines
Blood: Low blood potassium levels, metabolic alkalosis (increased alkalinity of the blood)
Others: Increased urination, tiredness

What are the other precautions for Disodium Hydrogen Citrate?

• The liquid forms of the drug contains sugar, it is advised to use with caution in diabetes patients

What are the Drug Interactions of Disodium Hydrogen Citrate?

• Since disodium hydrogen citrate makes the urine alkaline, it may increase the elimination of acidic drugs like salicylates and barbiturates through the urine, thus reducing their effects
• It may increase the blood sodium levels especially when taken with drugs like corticosteroids.
• Use with caution with diuretics like furosemide since it can cause metabolic disturbances.

What are the storage conditions for Disodium Hydrogen Citrate?

• It should be used stored at room temperature, keep it out of the reach of children

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Product Details

How does Disodium Hydrogen Citrate Syrup work?

Disodium Hydrogen Citrate works by making the urine more alkaline by neutralizing excess acid in the blood and urine.
Acidic urine is more prone to the growth of bacteria and thus urinary tract infections. By alkalizing urine, the growth of bacteria is inhibited and thus chances of UTI are reduced.

How to Take Disodium Hydrogen Citrate Syrup?

The dosage and duration of this medication should be taken as advised by the doctor. The dosage is based on your age, medical condition, and response to therapy.
Avoid taking disodium hydrogen citrate empty stomach.
Disodium Hydrogen Citrate should be taken along with plenty of fluids (water/juice etc) to prevent stomach upset.
In order to measure the prescribed dose, a medication measuring cup and not a household spoon should be used.
Shake the bottle well before each use.
If it is taken as over the counter product, check the label for directions before use.

Common Dosage for Disodium Hydrogen Citrate

Dosage is usually based on your condition as advised by the doctor. For best results, it should be taken at evenly spaced intervals.
Most recommended dose :
Adults – 15-30ml dissolved in water twice or thrice daily.
Children – 5ml dissolved in water twice or thrice daily.
Use with caution in infants and pregnant females.
Patients with pre-existing kidney disease and those suffering from dehydration should avoid using this syrup.
Never use more than the recommended dose or for longer periods of time without doctor’s consent.
In case of non improvement of symptoms or symptoms getting worse, seek medical attention immediately.

Also Read: Drotin Ds Dosage | Dexamethasone Uses | Diclofenac Sodium Dosage

Precautions- When to Avoid Disodium Hydrogen Citrate

Disodium Hydrogen Citrate Syrup should not be used in:

Allergy to any of its components
Patients with moderate to severe renal dysfunction (kidney disease)
Dehydrated patients
Patients with severe bacterial infection
Patients with high potassium levels
Patients with a heart problem (irregular heartbeat, heart failure)
Pregnant

Side Effects of Disodium Hydrogen Citrate Syrup

Majority of the patients do not show any side effects. However, few patients may show side effects with Disodium Hydrogen Citrate Syrup like:

Flatulence
Stomach cramps
Diarrhoea
Anxiety
Excessive production of urine
Gastrointestinal ulceration
Mood swings
Feeling of tiredness
In addition, it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.

What Are the Effects of Disodium Hydrogen Citrate on Organs?

Kidney – Disodium Hydrogen Citrate may be used cautiously in patients with kidney disease. In severe cases, dose adjustment may also be needed. Consult your doctors if any unwanted symptoms are observed.

Are There Any Reported Allergic Reactions?

Report to your doctor if you are allergic to any of its ingredients. Signs of allergic reaction include:

Rashes
itching of skin
Shortness of breath
Swelling of face, lips, tongue, or throat
Loss of consciousness

Drug Interactions to Be Careful About

All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/products you use. You must inform your doctor if you frequently use other drugs that make you drowsy or sleepy, such as sleeping pills, other allergy drugs, narcotic pain medicine, muscle relaxants, and drugs used for fits, depression, or anti-anxiety drugs. You must also inform about the herbal products that you are consuming. You must not modify the drug regimen without your doctor’s approval.

Disodium Hydrogen Citrate Syrup may interact with the following drugs and products:

Alcohol
Tetracycline
Barbiturates
Corticosteroids
Methotrexate
Potassium depleting diuretics
Amphetamines
Salicylates

Shows Effects / Results In

Disodium Hydrogen Citrate Syrup starts acting within a few minutes and the effect lasts for 4-6 hours.
A complete dose prescribed by your doctor must be taken for the complete cessation of symptoms from your body.

Storage Requirements for Disodium Hydrogen Citrate

Storage at room temperature away from direct light and heat unless mentioned in the package insert.
Do not freeze the medicine.
Keep medicinesaway from children and pets.

Pro Tips When Taking Disodium Hydrogen Citrate

Disodium Hydrogen Citrate is unsafe to use in patients with severe kidney disease and should be avoided or the dose should be altered as advised.

Also read about other medicine’s:  Dexorange | Deriphylline

FAQs

Is Disodium Hydrogen Citrate Syrup addictive?

No. However, self medication and dependence on these medicines should be avoided.

Can I have Disodium Hydrogen Citrate with alcohol?

Interaction with alcohol is unknown.
However, it may cause excessive drowsiness and calmness in few patients so alcohol should be consumed with caution along with Disodium Hydrogen Citrate.

Any particular food item to be avoided?

No.

Can I have Disodium Hydrogen Citrate when pregnant?

Disodium Hydrogen Citrate Syrup can be administered during pregnancy if advised by your doctor.
Always inform and consult your doctor if you are pregnant or plan to become pregnant for case specific recommendations.

Can I have Disodium Hydrogen Citrate when feeding a baby?

There is no evidence as to whether Disodium Hydrogen Citrate Syrup use has any side effect on lactating mother or baby.
Always inform your doctor if you are breast-feeding your child and use the medicine as advised.

Can I drive after taking Disodium Hydrogen Citrate?

If one experiences side effects like drowsiness, headache, dizziness or decrease in blood pressure, then it may not be advisable to drive a vehicle and operate heavy machinery while on this medication.

What happens if I overdose on Disodium Hydrogen Citrate Syrup?

It should not be administered in more than prescribed dose. Taking more medication or with increased frequency will not improve your symptoms earlier; rather it may cause serious side-effects.
If anyone is suspected of an overdosage, seek medical care immediately.

What happens if I take expired Disodium Hydrogen Citrate?

Taking a single dose may not cause any major adverse effect. However, the potency of the medicine may well have been reduced.
Please inform your physician regarding the same if expired medicines have been taken chronically for a longer duration.
To be on the safer side, always check and never use an expired drug.

What happens if I miss a dose of Disodium Hydrogen Citrate?

The medicine may not work well if you miss a dose because for effective working of the drug, a certain amount of drug must be present in your body at all times.
Always consume the missed dose as soon as you remember it. But, if it’s already time to take the second dose after that – do not take a double dose.
Disodium Hydrogen Citrate should always be taken following meals and with plenty of oral fluids or else chances of gastric side effects increases.
Patients on long term Disodium Hydrogen Citrate should be regularly monitored for electrolytes especially sodium and potassium.

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J011 | Натрий лимоннокислый 2-замещенный 1,5-водный

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Соответствие квалификации

—

Синоним на русском

Натрия цитрат 2-замещенный 1,5-водный

Наименование на английском

Sodium citrate dibasic sesquihydrate

Синоним на английском

di-Sodium Hydrogen Citrate 1 1/2-hydrate
Disodium hydrogen citrate sesquihydrate
Citric acid disodium salt
Sodium Citrate Dibasic

Агрегатное состояние/Внешний вид

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рН (3% раствора) 4,6-5,2
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